 |
|
学会・論文発表 |
|
Wave-front and Fourier Analysis of the High Myopia Transepithelial
PRK on Profile-500
Author（s）：Kodo Okuyama，Viktor Movshev
Hospital or Institution：Sangubashi Eye Clinic，IRTC Microsurgery
Address for Correspondence: 1-2-15-201 Higashigotanda Shinagawa-ku
Tokyo JAPAN
Tel : 81+3+34463902Fax : 81＋3＋3782178
Email：okuyama＠k.email.ne.jp
Purpose: To evaluate the predictability, safety, and long
term stability of transepithelial PRK for the correction of
the high and very high myopia and astigmatism using the Profile-500
Gaussian beam excimer laser.
Methods: We choose at random 10 patients，18 eyes，with high（8
eyes）and very high myopia（10eyes）．Among the 7 females and
3 males．Mean age was37.7 years. Before the transepithelial
PRK there was routine refractive examinations，contrast sensitivity
and endothelial cell counts. After the operation we tried
to evaluate the operation，using by KR-9000 PW Wavefront analyzer
and TMS-2N videokeratotopograph．
Results：Mean Spherical Equivalent before the operation was
-11.5+/-0.38D，after the operation was -1.75+/-0.42D. Three
eyes were operated twice due to haze classified as Fantes
1 to 2. Wavefront analyzer and Fourier Analysis show the appearance
of prismatic effect. There is not significant high order irregularity.
After the second operation all three eyes decrease haze level
to Fantes 0.5．
Conclusion : Ablation patterns of the Gaussian beam at a
given fluence level of the Profile-500 gives us aspherical
surfaces with optimal balance between defocusing and spherical
aberration for patient with high myopia. We can not see significant
reduction of contrast sensitivity. In some case with haze
for 3 to 12 months contrast sensitivity reduced, however after
disappearing of haze the contrast sensitivity returned to
the previous level.
Biochemical Investigations of Lacrima in Early Diagnosis
of Keratoconus
Author(s): Leonid Legkikh1, M. Koledintsev2, A. Semenova2,
K.Okuyama3
Hospital or Institution: 1. Svyatoslav Fyodorov S.I. Eye
Microsurgery complex, Beskudnikovsky Blvd.59A 127486, Moscow,
Russia Moscow, Russia
2. Moscow Medical Stomatological University, Moscow, Russia
3.Sangubashi Eye Clinic, Tokyo, Japan
Purpose: To study results of biochemical investigation of
lacrimal fluid in patients with initial keratoconus to develop
tests of early diagnosis of disease.
Methods: 26 patients with initial keratoconus aged from 16
to 44 years were examined The control group consists of 20
practically healthy people in the same age. The biochemical
investigation of lacrima was performed with the biochemical analyzer.
Results : The biochemical analysis of lacrima showed, that
an increase of activation of Lactate dehydrogenase, creatine
phosphokinase, amylase etc. These data in combination with
an increase of general protein and products of albuminolysis(urea, uric
acid) compared with the control group is notable for patients
with initial keratoconus.
Conclusion: The method of biochemical analysis of lacrimal
fluid can be used in the early diagnosis of keratoconus.
Immunologic Investigations of Lacrima in early Diagnosis Keratoconus
Author(s): Anna Semenova 1, M. Koledintsev 2, L. Legkikh
1, K. Okuyama 3
Hospital or Institution: Svyatoslav Fyodorov S.I."Eye
Microsurgery Complex
Address for Correspondence: Beskudnikovsky Blvd. 59A, 127486,
Moscow, Russia
E-mail :semenaru @yahoo.com
Tel: (095) 488-8424 Fax: (095) 905-5333
Purpose: To study results of immunologic investigations of
lacrima in patients with initialkeratoconus for development
of tests of early diagnosis of disease
Setting/Venue：1．Svyatoslav Fyodorov S.I. Eye Microsurgery
Complex，Moscow，Russia
2．Moscow Medical Stomatological University．
3．Sangubashi Eye Clinic，Tokyo，Japan．
Methods: 26 patients with initial keratoconus aged from 16
to 44 years were examined. The Control group consists of 20
practically healthy people of the same age. The immunologic
investigation of lacrima included a determination of concentration
of A，M，G immunoglobulins by method of Manchini G．Radial immunodiffusion．
Results: The immunologic investigation of lacrima showed
a significant Ig A increase in18 of 26 patients(69.2%). A
significant increase Ig G in 53.8%.
We noted a tendency to increase of Ig M compared with the
control. The difference was not significant. Thus, considerable
differences in the level of immune proteins of lacrima were
noted in patients with keratoconus compared with the control..
Conclusions: Methods of immunologic investigation of lacrima
can be used in the early diagnosis of keratoconus．
|
